Cyto-Fluid Fixative Solution

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Cyto-Fluid Fixative Solution

For Sputum, BAL & Bodily Fluids

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  • Cyto-Fluid Fixative Solution is a Saccomanno-type cytology fixative designed for the collection, preservation and transport of cellular material from sputum, bronchoalveolar lavage (BAL), bronchial washings and body-fluid specimens.
  • Its alcohol-based fixation system helps stabilize cellular morphology while polyethylene glycol helps protect cells from drying and supports efficient concentration of cellular material during cytological processing.
  • Saccomanno-type alcohol-based cytology fixative
  • Suitable for sputum, BAL, bronchial washings and body-fluid specimens
  • Helps preserve cellular morphology during specimen transport and processing
  • Minimizes air-drying-related cellular artifacts
  • Supports recovery and concentration of cells by centrifugation or filtration
  • Helps keep mucus and cellular material
  • Suitable for cytological preparation
  • Suitable for conventional cytology smear preparation
  • Ready-to-use formulation for convenient specimen collection and fixation
  • Suitable for short-term specimen holding and transport according to laboratory protocol
  • The alcohol component rapidly fixes and stabilizes cellular structures, helping preserve nuclear and cytoplasmic morphology. Polyethylene glycol (Carbowax) acts as a protective component that helps reduce drying-related changes and assists in maintaining cellular material during specimen processing.
  • After fixation, the specimen can be processed by appropriate laboratory methods such as centrifugation, filtration or cytocentrifugation, followed by preparation of cytology slides. Before staining, residual polyethylene glycol should be removed according to the laboratory’s validated processing procedure. Collection procedures commonly use centrifugation to concentrate the cellular sediment.
  • Excellent Cellular Preservation – Helps maintain recognizable nuclear and cytoplasmic morphology for cytological evaluation.
  • Reduced Air-Drying Artifacts – Helps protect specimens from drying-related morphological changes.
  • Efficient Cell Concentration – Facilitates recovery of cellular material from dilute or mucus-rich liquid specimens.
  • Improved Cytology Preparation – Supports preparation of concentrated, representative cellular deposits for microscopic examination.
  • Convenient Specimen Transport – Provides fixation and preservation during handling and transport.
  • Broad Cytology Application – Suitable for respiratory specimens and a range of liquid cytology samples.
  • Consistent Processing – Provides a standardized fixation medium for routine cytology workflows.
  • Typical Applications :
    1. 1. Sputum cytology
      2. Bronchoalveolar lavage (BAL)
      3. Bronchial washings
      4. Pleural fluid
      5. Peritoneal fluid
      6. Other suitable liquid cytology specimens
    Note: This fixation is particularly established for sputum and respiratory cytology. Published descriptions also document its use with urine, bronchial washings, pleural and peritoneal fluids and other liquid cytology specimens.

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